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Anbol® CARDIO, 100 mg, gastro-resistant tablets
acetylsalicylic acid
Read this leaflet carefully before you start taking this medicine because it contains information
that are important to you.
Always take this medicine exactly as stated in this leaflet or as explained to you by your doctor
or a pharmacist.
- Save the instructions. You may need to read it again.
- If you have additional questions or need advice, contact your pharmacist.
- If you experience any side effects, contact your doctor or pharmacist. This
includes any side effects not listed in this guide. See section 4.
- If you do not feel better or if you feel worse, you must contact your doctor.
In this guide you will read:
1. What is the drug Anbol CARDIO and what is it intended for
2. What you need to know before taking Anbol CARDIO
3. How to administer the drug Anbol CARDIO
4. Possible side effects
5. How to store Anbol CARDIO
6. Contents of the package and other information
1. What is the drug Anbol CARDIO and what is it for?
The drug Anbol CARDIO prevents the clogging and accumulation of blood platelets (thrombocytes) and in this way
prevents the formation of blood clots (thrombus) - inhibition of platelet aggregation.
The drug Anbol CARDIO is used:
• In preventing or preventing the formation of a blood clot after a heart attack or stroke
a repeat heart attack or stroke in patients who have already had these conditions
• This medicine may be prescribed to you if you have recently undergone bypass surgery (bypass surgery).
blood vessels of the heart so that the heart has enough blood flow)
2. What you need to know before taking Anbol CARDIO
You must not take Anbol CARDIO:
if you are allergic (hypersensitive) to acetylsalicylic acid, salicylates or any of the excipients
substances of this medicine (listed in section 6),
if you have previously used painkillers, increased body temperature or inflammation
(salicylates or other non-steroidal anti-inflammatory drugs) had an asthma attack or other reactions
hypersensitivity (allergic reactions),
if you have a stomach or duodenal ulcer,
if you have a pathological increased tendency to bleed (hemorrhagic diathesis),
if you have severe kidney weakness (insufficiency),
if you have severe liver failure,
if you have severe heart failure,
if you are simultaneously taking methotrexate (a medicine used to treat malignant or rheumatic diseases
conditions) in doses of 15 mg per week or higher,
in the last trimester of pregnancy,
in children and adolescents under 16 years of age, with the exception of prevention of thrombus formation (thrombosis)
during heart surgery.
Warnings and precautions
Talk to your doctor or pharmacist before taking the medicine:
if you are hypersensitive (allergic) to other painkillers (analgesics), anti-inflammatory drugs
(anti-inflammatory drugs) or drugs for the treatment of rheumatic conditions (antirheumatic drugs) or you have another
type of hypersensitivity,
if you have previously had stomach or intestinal ulcers, including chronic or recurrent ulcers,
if you have previously had bleeding in the stomach or intestines (bleeding in the digestive organs)
if you are using other medicines against blood clotting (anticoagulants) (see the section "Other
drugs and the drug Anbol CARDIO "),
if you have impaired kidney function or impaired cardiovascular function (e.g. renal
vascular diseases, congestive heart failure, volume depletion, major operations,
sepsis, or major hemorrhagic events), as acetylsalicylic acid may further increase the risk of
impairment of kidney function and acute renal weakness,
caution is required if you have red blood cell disease (glucose-6-phosphate enzyme deficiency
dehydrogenase), because acetylsalicylic acid can cause destruction of red blood cells with
release of hemoglobin (hemolysis or hemolytic anemia). Factors that can increase the risk of
hemolysis are e.g. large dose, elevated body temperature or acute infection.
if you have impaired liver function,
if you use non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen (drugs
against pain, increased body temperature and inflammation) (see the section "Other drugs and the drug Anbol
CARDIO "),
if you have bronchial asthma, pollen allergy, swelling of the nasal mucosa (nasal polyps) or chronic
a disease of the respiratory organs or you show signs of a hypersensitivity reaction to other substances.
If you are planning surgery (including minor procedures, such as tooth extraction), tell your doctor or
to the dentist if you have taken the drug Anbol CARDIO, because there may be an increased tendency to bleeding.
If you cut or injure yourself, the bleeding may take longer than usual. It has to do with action
drug Anbol CARDIO. Minor cuts or injuries (eg while shaving) are usually insignificant. If
notice unusual bleeding (in an unusual place or if the bleeding lasts an unusually long time), seek
doctor's help.
In small doses, acetylsalicylic acid reduces the excretion of uric acid. This can cause
gout attacks in patients who have a predisposition to it.
Children and adolescents
The drug Anbol CARDIO must not be used in children and adolescents under the age of 16 in the case of viral infections
infection (e.g. flu) with or without elevated body temperature, unless you first seek medical advice.
With certain viral diseases, especially influenza A, influenza B and chicken pox, there is a risk of Ray's
syndrome (a very rare disease that can be life-threatening and requires immediate medical intervention).
The risk may be higher if acetylsalicylic acid is given as a concomitant therapy; however, it has not been proven
cause and effect relationship. If persistent vomiting occurs in such diseases, it may be a sign of Ray's disease
syndrome.
Other drugs and the drug Anbol CARDIO
Tell your doctor or pharmacist if you are taking, have recently taken or might take any
other medicines, including those that can be obtained without a doctor's prescription.
The drug Anbol CARDIO, administered in high doses and at the same time as the drugs listed below, can have an effect
to the manifestation of side effects of those drugs.
The drug Anbol CARDIO can increase the effect and increase the risk of side effects of the following drugs:
Methotrexate (a medicine used to treat carcinoma (cancer) and certain rheumatic diseases) -
increased toxicity of methotrexate on the liver.
NSAIDs (non-steroidal anti-inflammatory drugs; drugs against pain, elevated body temperature or
inflammation) and other antirheumatic drugs (medicines against rheumatism) in general: increased risk of ulcers and
gastrointestinal bleeding.
Anticoagulants (medicines against blood clotting), thrombolytics (medicines for breaking down blood
clot) or other drugs that prevent the accumulation of blood platelets: increased risk
from bleeding; if you are taking these medicines, pay attention to the appearance of signs of external or
internal bleeding (eg bruises).
Selective serotonin reuptake inhibitors (medicines to treat depression): increased risk
from bleeding in the digestive organs.
Digoxin (medicine to strengthen the heart): increased concentration of digoxin in the blood.
Antidiabetic drugs (eg insulin, sulfonylurea): reduction of blood glucose levels.
Systemic glucocorticoids (cortisone/corticosteroids/steroids taken orally or via
injections) except for hydrocortisone used as replacement therapy in Addison's disease: increased
the risk of overdose with acetylsalicylic acid after treatment with these drugs has ended.
Valproic acid (a drug used to treat epilepsy): increased valproic toxicity
acid.
Alcohol: increased bleeding in the digestive organs and prolonged bleeding time.
If you take the following medicines, Anbol CARDIO can reduce their effect:
Some NSAIDs (non-steroidal anti-inflammatory drugs), such as ibuprofen and naproxen: reduce
the effect of the drug Anbol CARDIO, which leads to reduced clotting of blood platelets (platelets) and
preventing the formation of a blood clot (thrombus): in this way, the effect of the drug Anbol can be limited
CARDIO to prevent heart attack or stroke.
Diuretics (drugs that increase urine output): reduced filtering of blood in the kidneys.
4 out of 7
Systemic glucocorticoids (cortisone/corticosteroids/steroids taken orally or via
injections), except for hydrocortisone, which is used as replacement therapy in Addison's disease:
decreased value of acetylsalicylic acid in the blood.
ACE (angiotensin converting enzyme) inhibitors - a group of drugs for lowering blood pressure:
reduced blood filtration in the kidneys and reduced blood pressure lowering effect.
Uricosurics (medicines used in the treatment of gout and which accelerate the excretion of uric acid,
for example. benzbromarone, probenecid): reduced excretion of uric acid, which can lead to
gout attacks.
You should not take the drug Anbol CARDIO if you are simultaneously taking any of the above-mentioned drugs,
unless your doctor tells you otherwise.
Taking Anbol CARDIO with alcohol
Do not take Anbol CARDIO with alcohol.
Pregnancy, breastfeeding and fertility
If you are pregnant or breastfeeding, think you are pregnant or are planning to become pregnant, contact your doctor or
pharmacist for advice before taking this medicine.
Pregnancy
If you find that you are pregnant during treatment with Anbol CARDIO, inform your doctor immediately
doctor.
During the first and second trimester of pregnancy, you can only use the drug Anbol CARDIO if it is prescribed by your doctor
prescribed.
Breastfeeding
The drug Anbol CARDIO is excreted in small amounts in breast milk. About the use of the drug during breastfeeding
consult a doctor. If you take the drug Anbol CARDIO as a regular therapy or in the case of prolonged therapy
use or the use of large doses, you should stop breastfeeding.
Driving vehicles and operating machines
The drug Anbol CARDIO does not affect the ability to drive a vehicle and operate machinery.
3. How to take the drug Anbol CARDIO
Always take this medicine exactly as stated in this leaflet or as explained to you by your doctor
doctor. If you are not sure, check with your doctor or pharmacist.
In the treatment of heart or blood-brain diseases:
Before the first use of the drug in the indicated indications, it is necessary to consult a doctor. Usual dosage
during long-term use of acetylsalicylic acid is 100 mg once a day. In some cases
a higher dose may be appropriate, especially for short-term use of the drug, up to 300 mg according to the doctor's advice
daily. In general, acetylsalicylic acid should be used with caution in elderly patients who are
more susceptible to the occurrence of unwanted events. The usual adult dose is recommended for patients who do not have
severe kidney or liver weakness (see the sections "Do not take Anbol CARDIO" and "Warnings and precautions
of caution"). Therapy should be monitored at regular intervals.
Antithrombotic effect:
The recommended daily dose is 100 mg. Tablets taken at the time of diagnosis should be
I will chew so that they are absorbed faster.
Children and adolescents:
The drug must not be used in children and adolescents under the age of 16, unless it is indicated (e.g.
in Kawasaki disease). See the section "You must not take Anbol CARDIO".
Method of application:
The drug Anbol CARDIO is intended for oral use. Gastro-resistant tablets should be taken whole
plenty of water, preferably before a meal (at least 30 minutes before a meal).
If you have taken more Anbol CARDIO than you should If you (or someone else) have taken more than you should
should, inform the doctor immediately or go to the nearest emergency department. Your doctor will carry out the necessary measures in
according to the degree of severity of overdose/poisoning.
Symptoms of moderate poisoning may include lightheadedness, dizziness, tinnitus (ringing in the ears),
hearing impairment, sweating, nausea and vomiting, headache and confusion.
Severe overdose (possibly life-threatening) can lead to rapid breathing (hyperventilation), elevated
body temperature, excessive sweating, dehydration (feeling thirsty), restlessness, convulsions (convulsions),
reduced blood sugar levels, coma and shock (collapse of circulation) and respiratory arrest.
If you forgot to take Anbol CARDIO
Do not take a double dose to make up for a missed dose. Continue to take the medicine according to
with this instruction or as advised by your doctor.
If you suddenly stop taking Anbol CARDIO
Do not stop treatment with Anbol CARDIO without first consulting your doctor.
If you have any further questions about the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
patients taking this medicine.
Digestive system disorders:
– Digestive problems such as heartburn, discomfort and stomach pain
- Bleeding. With long-term use of the drug Anbol CARDIO, hidden (occult) bleeding from
digestive organs that can cause anemia due to iron deficiency. If you notice a dark discolouration
stools or vomit blood (symptoms of serious stomach bleeding), you must see a doctor immediately.
– Ulcers which in very rare cases can lead to perforation (rupturing of the ulcer)
- Ignition
Blood disorders:
– Bleeding, e.g. bruising, nosebleeds, bleeding gums, skin bleeding or urinary bleeding
tract or genitalia, possibly with prolonged bleeding time.
– Hemolysis and hemolytic anemia in patients with severe glucose-6-phosphate dehydrogenase deficiency
(G6PD) (see section 2 "What you need to know before you take Anbol CARDIO")
- Rare to very rare serious bleeding, such as bleeding in the brain, especially in patients with
uncontrolled high blood pressure and/or in patients who simultaneously take medicines for
blood thinning (anticoagulants). In individual cases, this can be life-threatening.
Kidney disorders:
Kidney function disorder, renal weakness.
Immune system disorder:
Hypersensitivity reactions, drug hypersensitivity reactions, allergic edema and angioedema, anaphylactic reaction
including shock with appropriate laboratory findings and clinical manifestations.
Hypersensitivity reactions on the skin (rash, hives, itching), reactions of the respiratory system, digestive system and
reactions of the cardiovascular system, especially in asthmatics.
Symptoms can be: drop in blood pressure, attacks of difficulty breathing, runny nose, stuffy nose, swelling
face, tongue and larynx.
Cardiac disorders:
Cardio-respiratory distress syndrome (severe heart and lung disease).
Liver disorders:
Impairment of liver function, increased value of liver enzymes - transaminase.
Nervous system disorders:
Dizziness and ringing in the ears (tinnitus) may be signs of an overdose.
Respiratory, thoracic and mediastinal disorders:
Analgesic-induced asthma syndrome.
Precautionary measures
If you experience any of the previously mentioned side effects, stop taking the medicine
Anbol CARDIO.
Contact your doctor who will determine the severity of the adverse reaction/s and decide on
further measures. At the first appearance of symptoms of hypersensitivity, stop taking the drug.
If any side effect becomes serious or you notice any side effect not listed in
this instruction, please inform your doctor or pharmacist about it.
Reporting adverse reactions
If you experience any unwanted reaction, you should inform your doctor or pharmacist.
This includes any possible side effects that are not listed in this guide. By signing up
adverse reactions can help evaluate the safety of this medicine. They suspect unwanted reactions
you can report to the Agency for Medicines and Medical Devices of Serbia (ALIMS):
Agency for Medicines and Medical Devices of Serbia
National Center for Pharmacovigilance
Vojvode Stepe 458, 11221 Belgrade
Republic of Serbia
website: www.alims.gov.rs
e-mail: nezeljene.reakcije@alims.gov.rs
5. How to store Anbol CARDIO
Keep the medicine out of the sight and reach of children.
You must not use Anbol CARDIO after the expiration date indicated on the outer packaging
after "Valid until:". The expiration date refers to the last day of the specified month.
Store at a temperature of up to 25 °C. Do not store in the refrigerator.
Unusable medicines are handed over to the pharmacy where the notice that they are to be collected is displayed in that pharmacy
unusable medicines from citizens. Unusable medicines must not be thrown into the sewer or together with
communal waste. These measures will help protect the environment.
6. Package contents and other information
What does Anbol CARDIO contain?
The active substance is acetylsalicylic acid.
One gastro-resistant tablet contains 100 mg of acetylsalicylic acid.
Auxiliary substances are:
Tablet core: cellulose, powder; starch, corn, pregelatinized
Tablet film (coating): Acryl -Eze Clear (93F19255) composition: methacrylic acid copolymer type C; talcum powder;
macrogol 8000; silicon dioxide, colloidal, anhydrous; sodium hydrogen carbonate; sodium lauryl sulfate.
What does Anbol CARDIO look like and the contents of the package
Gastro-resistant tablet.
Round, white, biconvex, coated tablets.
The inner packaging is a blister (PVC/Al) with 15 gastro-resistant tablets.
The outer packaging is a collapsible cardboard box containing 2 blisters with 15 gastro-resistant tablets each
(a total of 30 gastro-resistant tablets) and Instructions for the drug.
License holder and manufacturer
License holder:
Galenika ad Belgrade
Batajnički road bb, Belgrade
Republic of Serbia
Manufacturer:
FARMALIDER, SA,
C/ Aragoneses, 2, Alcobendas, 28108 Madrid, Spain
This instruction was last approved
July, 2020.
Mode of administration of the drug:
The drug is issued without a doctor's prescription.
License number and date:
515-01-03339-19-01 from 23.07.2020.
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Note: We strive to be as accurate as possible in the description of all products, but we cannot guarantee that all descriptions are complete and error-free. Thank you for your understanding.
All items shown on the site are part of our offer, but it does not imply that they are available at all times
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